Bifurcation Lesions in ST-Segment Elevation Myocardial Infarction (STEMI): The Double Stent Technique: Is it Still a Risk Factor for Stent Thrombosis (ST)?

Gabriel Greenberg Cardiology, Rabin Medical Center, Petach-Tikva, Israel Ran Kornowski Cardiology, Rabin Medical Center, Petach-Tikva, Israel Hana Vaknin Assa Cardiology, Rabin Medical Center, Petach-Tikva, Israel Tamir Bental Cardiology, Rabin Medical Center, Petach-Tikva, Israel Eli Lev Cardiology, Assuta, Ashdod, Israel Abid Samara Cardiology, Rabin Medical Center, Petach-Tikva, Israel Lior Perl Cardiology, Rabin Medical Center, Petach-Tikva, Israel Pablo Codner Cardiology, Rabin Medical Center, Petach-Tikva, Israel Abid Assali Cardiology, Rabin Medical Center, Petach-Tikva, Israel

Background and Objectives: STEMI is associated with a pro-thrombotic milieu and as such treatment of bifurcation lesions is aimed towards the provisional strategy, avoiding 2-stent approach a priori. We sought to compare one vs. 2-stent approach as treatment options for STEMI involving bifurcation lesions.

Methods: We analyzed 204 consecutive patients presenting with STEMI involving bifurcation lesions who underwent primary PCI at our center between 2002-2017. Patients were allocated into 2 groups based on the strategy used, e.g. one vs. two-stent approach. We compared their demographic and angiographic characteristics and the effects of strategy on clinical outcomes after one year.

Results: Patients in both groups were of similar age and gender. There was no difference in the location of bifurcation lesions and in the LV ejection fraction (EF).

Table I

1-Stent

n=126

2-Stents

n=78

p-Value

Age (years)

62±13

61±12

0.5

Male (%)

84

79

0.8

Left Main (%)

8.7

15.4

0.2

LAD (%)*

63

50

0.2

LCX (%)*

14

22

0.2

RCA (%)*

14.3

17.8

0.2

LVEF (%)

44±11

44±11

0.9

Kissing Balloon Inflation (%)

60

86

0.001

*LAD- Left anterior descending, LCx- Left circumflex, RCA- Right coronary artery

Outcomes were similar in both strategies at all time points (Table II).

1Year Outcomes

1-Stent

n=126

2-Stents

n=78

p-Value

Death rate (%)

4.0

8.9

0.1

Recurrent MI (%)

5.6

1.3

0.1

Stent Thrombosis (%)

3.2

2.6

0.8

Target Vessel Revascularization (%)

7.9

10.4

0.5

Major Adverse Cardiovascular Events (%)

17.7

19.5

0.2

Conclusions: Our study shows that in case of need, the 2-stent strategy for bifurcation lesions during STEMI is not associated with increased risk for subsequent adverse angiographic or clinical events compared to a single provisional stenting technique.

Gabriel Greenberg
Gabriel Greenberg
גרינברג
בי"ח בילינסון








Powered by Eventact EMS