Background and Objectives: STEMI is associated with a pro-thrombotic milieu and as such treatment of bifurcation lesions is aimed towards the provisional strategy, avoiding 2-stent approach a priori. We sought to compare one vs. 2-stent approach as treatment options for STEMI involving bifurcation lesions.
Methods: We analyzed 204 consecutive patients presenting with STEMI involving bifurcation lesions who underwent primary PCI at our center between 2002-2017. Patients were allocated into 2 groups based on the strategy used, e.g. one vs. two-stent approach. We compared their demographic and angiographic characteristics and the effects of strategy on clinical outcomes after one year.
Results: Patients in both groups were of similar age and gender. There was no difference in the location of bifurcation lesions and in the LV ejection fraction (EF).
Table I |
1-Stent n=126 |
2-Stents n=78 |
p-Value |
Age (years) |
62±13 |
61±12 |
0.5 |
Male (%) |
84 |
79 |
0.8 |
Left Main (%) |
8.7 |
15.4 |
0.2 |
LAD (%)* |
63 |
50 |
0.2 |
LCX (%)* |
14 |
22 |
0.2 |
RCA (%)* |
14.3 |
17.8 |
0.2 |
LVEF (%) |
44±11 |
44±11 |
0.9 |
Kissing Balloon Inflation (%) |
60 |
86 |
0.001 |
*LAD- Left anterior descending, LCx- Left circumflex, RCA- Right coronary artery
Outcomes were similar in both strategies at all time points (Table II).
1Year Outcomes |
1-Stent n=126 |
2-Stents n=78 |
p-Value |
Death rate (%) |
4.0 |
8.9 |
0.1 |
Recurrent MI (%) |
5.6 |
1.3 |
0.1 |
Stent Thrombosis (%) |
3.2 |
2.6 |
0.8 |
Target Vessel Revascularization (%) |
7.9 |
10.4 |
0.5 |
Major Adverse Cardiovascular Events (%) |
17.7 |
19.5 |
0.2 |
Conclusions: Our study shows that in case of need, the 2-stent strategy for bifurcation lesions during STEMI is not associated with increased risk for subsequent adverse angiographic or clinical events compared to a single provisional stenting technique.